Penny stocks are known for sharp moves—and on Tuesday three names stand out. According to the latest data, reAlpha Tech Corp. (AIRE), ProMIS Neurosciences (PMN), and Incannex Healthcare (IXHL) were the top penny stocks to watch, driven by high dollar volume and major news.
These stocks all trade under $5 and have market caps below $300 million—but each one made serious noise on Wall Street this week.
reAlpha Tech Corp. (AIRE) | +347.21%
- Sector: Real Estate Technology
- Dollar Volume: $670.98 million
- Stock Price: $0.35 (after Monday’s spike)
Why it moved: reAlpha announced it entered definitive agreements to sell 14.29 million shares at $0.35 in a registered direct offering. The deal is expected to raise $5 million, funding working capital and general corporate needs.
That sparked a massive 347% surge in share price, making AIRE the most traded penny stock of the day.
ProMIS Neurosciences (PMN) | +154.49%
- Sector: Biotech / Neuroscience
- Dollar Volume: $325.25 million
- Stock Price: Under $1 (pre-market rally hit +177%)
Why it moved: The FDA granted Fast Track designation for PMN310, a drug candidate for Alzheimer’s disease. PMN310 is now in a Phase 1b trial, with key interim results expected in Q2 2026.
This bullish catalyst caused PMN shares to skyrocket, with analysts maintaining a Moderate Buy rating and a projected upside of 695% from current levels.
Incannex Healthcare Ltd. (IXHL) | +34.43%
- Sector: Biopharmaceuticals
- Dollar Volume: $287.61 million
- Stock Price: $0.65–$0.80 range
Why it moved: There was no specific news for IXHL on Monday, but trading volume and price jumped significantly—possibly driven by momentum trading or speculative buying tied to broader biotech enthusiasm.
The company focuses on treatments for sleep apnea, anxiety, and arthritis—key chronic markets with unmet needs.
Why Penny Stock Volume Matters
Dollar Volume = share price × number of shares traded. It’s a strong indicator of institutional or retail interest—especially when paired with sharp price moves like these.
All three stocks appeared at the top of TipRanks’ Penny Stock Screener, which tracks daily breakouts using real-time data.
Reminder for Investors
Penny stocks are volatile and risky. But when backed by catalysts like FDA approvals, earnings announcements, or private offerings, they can deliver short-term gains—and, occasionally, long-term upside.
Before investing, always check:
- Analyst ratings
- Insider buying activity
- Recent filings or news
- Liquidity and float levels