AstraZeneca investing $2B in manufacturing in Maryland to advance biologics manufacturing

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‘This is the single largest private investment in the state of Maryland in at least the past 10 years.’

WBAL-TVDavid Collins

AstraZeneca Frederick Manufacturing Center

SOURCE: WBAL-TVDavid Collins

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AstraZeneca investing $2B in manufacturing in Maryland to advance biologics manufacturing

‘This is the single largest private investment in the state of Maryland in at least the past 10 years.’

Updated: 2:26 PM EST Nov 21, 2025

Editorial Standards

AstraZeneca is investing $2 billion in manufacturing in Maryland that will support 2,600 jobs, state and company officials announced Friday.The company is expanding its operations in Maryland at its flagship biologics manufacturing facility in Frederick and will build a new state-of-the-art facility in Gaithersburg for the development and clinical supply of innovative molecules to be used in clinical trials.”This is really a landmark moment for AstraZeneca and the state of Maryland,” AstraZeneca CEO Pascal Soriot said. “This announcement today is really near and dear to our heart because Maryland is really home to AstraZeneca in the United States. This is where we have the heart of the company in the United States.”Maryland Gov. Wes Moore said the state is kicking in a 10% investment match to support the expansion.”This is the single largest private investment in the state of Maryland in at least the past 10 years,” Moore said. “Partnership produces progress, nothing else ever will. The history made today will lift up Marylanders from all walks of life.”The Frederick facility currently produces medications for cancer, autoimmune, respiratory and rare disease treatments. The planned expansion will nearly double commercial manufacturing capacity, which will increase the supply of existing medicines and, for the first time, begin production of AstraZeneca’s rare disease portfolio.The company said its Frederick expansion will create 200 highly skilled jobs and 900 construction roles. The Gaithersburg facility is expected to create an additional 100 jobs, retain 400 roles and support a further 1,000 construction-related jobs. Both facilities are expected to be operational in 2029.The announcement is part of AstraZeneca’s $50 billion investment announced in July and follows a series of U.S. commitments over the past six months, including unveiling a new cell therapy manufacturing facility in Rockville.Watch the announcement as it streamed live on the WBAL-TV 11 News YouTube Channel:

AstraZeneca is investing $2 billion in manufacturing in Maryland that will support 2,600 jobs, state and company officials announced Friday.

The company is expanding its operations in Maryland at its flagship biologics manufacturing facility in Frederick and will build a new state-of-the-art facility in Gaithersburg for the development and clinical supply of innovative molecules to be used in clinical trials.

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“This is really a landmark moment for AstraZeneca and the state of Maryland,” AstraZeneca CEO Pascal Soriot said. “This announcement today is really near and dear to our heart because Maryland is really home to AstraZeneca in the United States. This is where we have the heart of the company in the United States.”

Maryland Gov. Wes Moore said the state is kicking in a 10% investment match to support the expansion.

“This is the single largest private investment in the state of Maryland in at least the past 10 years,” Moore said. “Partnership produces progress, nothing else ever will. The history made today will lift up Marylanders from all walks of life.”

The Frederick facility currently produces medications for cancer, autoimmune, respiratory and rare disease treatments. The planned expansion will nearly double commercial manufacturing capacity, which will increase the supply of existing medicines and, for the first time, begin production of AstraZeneca’s rare disease portfolio.

The company said its Frederick expansion will create 200 highly skilled jobs and 900 construction roles. The Gaithersburg facility is expected to create an additional 100 jobs, retain 400 roles and support a further 1,000 construction-related jobs. Both facilities are expected to be operational in 2029.

The announcement is part of AstraZeneca’s $50 billion investment announced in July and follows a series of U.S. commitments over the past six months, including unveiling a new cell therapy manufacturing facility in Rockville.

Watch the announcement as it streamed live on the WBAL-TV 11 News YouTube Channel:

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